ABSTRACT The present work evaluated the immunomodulatory effect of thalidomide (Thal) at different doses on tumor-associated macrophages (TAMs) using a mouse model of human breast cancer.Mice were inoculated with 4T1 cells in the left flank and treated with Thal once a day at concentrations of 50, 100, and 150mg/kg body weight from the 5th day unti
The COVID-19 pandemic emerged as a largely unexplained outbreak of pneumonia Overflow Grill cases, in Wuhan City, China and rapidly spread across the world.By 11th March 2020, WHO declared it as a global pandemic.The resulting restrictions, to contain its spread, demanded a momentous change in the lifestyle of the general population as well as canc
The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection of a neuron.Under normal conditions two axonal cytoskeletal polymers, microtubules and neurofilaments, align longitudinally in axons and are interspersed in axonal cross-sections.However, in many neurotoxic and neurode
The high degree of encephalization characterizing modern birds is the product of a long evolutionary history, our understanding of which is still largely in its infancy.Here we provide a redescription of the endocranial space of the oviraptorosaurian dinosaur Auto Feed Conchoraptor gracilis with the goal of assessing the hypothesis that it shares u